Shelley Darlingson (the indomitable Anna Faris) was delivered in a basket to an orphanage and then remained the only one who was never adopted. She blooms at late adolescence and then at 18 becomes a Playboy Bunny. She has never made a centrefold, but she still wants to live there forever.
After her birthday party she is told she has reached the dark old age of 59 - as counted by those in charge of the mansion in Illinois ruled by centenarian Hugh Hefner actually playing himself - there are many others spattered through this film who are playing themselves, including real bunnies and others.